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OCR: d with The possible aetiological factors associ In the thyroid carcinoma are listed in Fig. 16. Bre past, the two major aetiological factors thought to be iodine deficiency with it f accompanying maintained stimulatio thyroid-stimulating hormone (TSH), noma. malignant change in a long-standing med any Epidemiological surveys have not con excess incidence of thyroid malignanc s that iodine-deficient areas. Current opinion e a rare follicular malignant change in an adenoma mu event since adenomas are common a carcinomas